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To overcome these resistance mechanisms in
2019-06-05
To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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br Conflict of interest br Case presentation A year
2019-06-05
Conflict of interest Case presentation A 64-year-old female presented to the emergency room with persistent dizziness that began early that morning. She had a 30-year history of palpitations and known electrocardiogram (ECG) abnormalities. Her pulse was irregular at 130–270min−1 and blood pres
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After the success of the Millennium Development Goals
2019-06-01
After the success of the Millennium Development Goals and the reduction in more than 50% of child mortality in children younger than 5 years (Countdown to 2015 report), the survive and thrive motto was given prominence by the Sustainable Development Goals (SDGs). For all children to thrive, we need
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order SB 203580 hydrochloride For the relationship between t
2019-06-01
For the relationship between the PVAB and FFRWs, setting the PVAB period as short as possible is considered optimal, because not all patients necessarily have problems with FFRWs [4,6]. However, the Medtronic pacemakers investigated in this study had minimum PVAB values as short as 110ms or 130ms, w
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A first step is reconsideration
2019-06-01
A first step is reconsideration of the term family planning. This debate is not simply a question of semantics—language is a powerful ideological and political statement. Discourse creates a representation of the world; it perpetuates a cultural and social reality. In this sense, language is action,
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En cuanto a la Accountability horizontal Przeworski plante q
2019-06-01
En cuanto a la Accountability horizontal, Przeworski planteó que O’Donnell utilizaba el concepto para referirse a que en América Latina las relaciones interinstitucionales, los pesos y contrapesos entre poderes e instancias del Estado eran débiles, por lo cual se terminaban delegando las decisiones
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Introduction Acute erythroleukemia AEL is
2019-06-01
Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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N-(p-amylcinnamoyl) Supplier The option tested by Berkley an
2019-06-01
The option tested by Berkley and colleagues is the use of prolonged antimicrobial prophylaxis after clinical nutritional recovery. The concept of empirical broad-spectrum antimicrobial therapy in high-risk immunocompromised populations is not novel, as there have been decades now of demonstrated ben
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br Materials and methods This study included WCD patients
2019-05-31
Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate stearoyl-coa desaturase of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with low left vent
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Emergency care inherently addresses the wide array
2019-05-31
Emergency care inherently addresses the wide array of illness and injury, including traumatic injuries, surgical disease, acute complications of chronic illness (eg, strokes, myocardial infarction, diabetic ketoacidosis, complications of HIV, tuberculosis, hepatitis C, and other chronic infections),
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br In Anand Bhopal s discussion March of health inequalities
2019-05-31
In Anand Bhopal\'s discussion (March, 2015) of health inequalities, social determinants of health, and advocacy for social change in health care in the 21st century, we were disappointed to see little recognition of the branch of medicine that congo red epitomises “societal doctors”: public healt
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Un caso importante de esa etapa es el movimiento
2019-05-31
Un caso importante de esa etapa es el movimiento cocalero, el mismo que decide participar electoralmente pero no logra acuerdo respecto prolyl hydroxylase inhibitor la mejor fórmula y se divide en dos grupos distintos. Por un lado, los cocaleros del Valle del río Apurímac, que optan por construir el
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No livro de fato a aproxima o aparece muito mais
2019-05-31
No livro, de fato, aldose reductase inhibitors aproximação aparece muito mais como uma metáfora do que como um tratado. Tudo parece girar em torno da palavra intuição ou de uma ideia de sensação. Algo a ver com o inexplicável. “ por que, ao entrar no quarto onde esse homem passa seus dias recluso [o
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Evidence of a variant induction of apoptosis
2019-05-31
Evidence of a variant induction of apoptosis to vorinostat in different DLBCL cell lines according to HAT mutational status implies that defects in CREBBP/EP300 could potentially explain the heterogeneous observations in clinical trials of vorinostat in NHL. These findings, however, need to be confi
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br Introduction Aplastic anemia AA
2019-05-31
Introduction Aplastic anemia (AA) is a rare disease characterized by pancytopenia and a hypocellular bone marrow. Specific cytogenetic abnormalities, monosomy 7 and trisomy 8, are frequently associated with clonal evolution [1]. Clonal cytogenetic abnormalities also may be present with hypocellul
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