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Furthermore we found that expression of two C
2019-08-24

Furthermore we found that expression of two C1 nodule cysteine proteases, Glyma.06G283100 and Glyma.06G174800, changed very little under drought despite the two proteases having similarity to the Arabidopsis senescence-related SAG12 gene with 62% similarity by Glyma.06G283010 and 58% by Glyma.06G174
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These contrasting results observed with intra
2019-08-24

These contrasting results observed with intra-BNST combined injections of NOC-9 and CP 376395 on freezing (in the novel arena) versus anxiety-related behavior (in the EPM) suggest that CRF neurotransmission within this forebrain limbic site could be mainly involved in the modulation of more subtle a
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In recent years neuroimaging studies have
2019-08-24

In recent years, neuroimaging studies have increasingly demonstrated acute effects of THC on mtor pathway function, the vast majority of them involving a cognitive challenge (Bossong et al., 2014b). For example, without affecting performance accuracy, THC caused reductions in activity during encodi
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Mohan et al found no improvement of the strength
2019-08-24

Mohan et al. [8] found no improvement of the strength of the bricks due to addition of waste RHA. Hossain et al. [9] collected RHA from a local rice mill, where rice husk was burnt in an uncontrolled environment, and then used for replacement of clay in brick production. With inclusion of RHA water
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ERRGO mice exhibited increased oxygen consumption
2019-08-24

ERRGO mice exhibited increased oxygen consumption, decreased RER, high running endurance, and resistance to diet-induced weight gain. These changes are physiological hallmarks of increased aerobic capacity in mice and are a direct consequence of engineering highly oxidative and vascularized muscle b
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The acid base properties of the
2019-08-24

3. The acid-base properties of the IL are important issues to consider because protonation changes caused by Brønsted-acidic or basic ions may result in enzyme deactivation [29]. Thereby, the acid-base properties of the newly designed IL need proper control for enzymes by selection of appropriate ca
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br Materials and methods br Results br Discussion
2019-08-24

Materials and methods Results Discussion In rodent species, CYP2E1 and CYP2B have been implicated in CCl4 metabolism. In this study, we used expressed human CYP2E1 to show that this enzyme is a high-affinity catalyst responsible for low-dose CCl4 metabolism. Studies employing an inhibitory
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Gap19 reviews Verapamil a calcium channel blocker used
2019-08-24

Verapamil, a calcium channel blocker used clinically as a coronary vasodilator, was amongst the first compounds identified that could reverse MDR and potentiate the effects of MDR1 substrates such as vincristine [15], [16]. Verapamil, along with a number of other MDR1 blockers, have proved largely u
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The Penicillium strain used in
2019-08-23

The Penicillium strain used in this work was isolated from Atlantic forest soil and previously screened as lipase producer (Tauk-Tornisielo et al., 2005). The immobilization was previously evaluated using hydrophobic supports, i.e. agarose based butyl-(But), phenyl-(Phe) and octyl-Sepharose (Oct), a
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br Results br Discussion The process
2019-08-23

Results Discussion The process by which MBCs differentiate from GC B cell precursors remains mostly uncharacterized, in large part because of the uncertainty surrounding the nature of the precursor rb 1 within the GC. The identification here of a distinct subset of GC B cells, CCR6+ LZ B cell
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To function as Ub ligases E proteins must interact with
2019-08-23

To function as Ub-ligases, E3 proteins must interact with E2s. As compared to the extensive studies on E3s, functional studies on E2s are relatively rudimentary in higher plants. We previously reported that there are 48 genes encoding Ub-conjugating (UBC) fold-containing putative E2 proteins in the
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Tailoring pharmacological treatment to the genetic backgroun
2019-08-23

Tailoring pharmacological treatment to the genetic background of a person can enhance therapeutic response (), increase compliance (), and decrease drug toxicity (, , ). Because cocaine addiction has a strong genetic basis, with the vulnerability to develop an addiction estimated to be as high as 72
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Homologous recombination HR has important roles in the repai
2019-08-23

Homologous recombination (HR) has important roles in the repair of stalled or collapsed DNA replication forks, as well as of DNA double-strand breaks. Among the factors required for HR in human Gabapentin are RAD51, BRCA1, and BRCA2 (Davies et al., 2001, Sung and Klein, 2006, Xia et al., 2001). BRCA
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Analysis of Table shows that
2019-08-23

Analysis of Table 1 shows that compound 7b, in which the biphenyl scaffold does not bear any substituent, displays its inhibitory potency in the micromolar range (IC50 = 11 μM). If the amide bridge is moved from position 1 to 3 of the biphenyl system, product 7c is yielded, whose potency is about 4
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N fowleri enters the host through the nasal cavity and
2019-08-23

N. fowleri enters the host through the nasal cavity and travels via the olfactory nerve into the endothelin receptor where it causes PAM (Visvesvara and Stehr-Green, 1990). The ameba most commonly infects healthy young adults and children and is able to evade the immune system but also elicits exte
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