• X-press Tag Peptide: Precision Tools for Neddylation and ...

  2025-09-29

  Explore the advanced utility of X-press Tag Peptide as a protein purification tag peptide in dissecting neddylation and mTORC1 signaling. This in-depth article uniquely connects biochemical features with emerging applications in cancer and metabolic disease research.

• Influenza Hemagglutinin (HA) Peptide: Next-Generation Tag...

  2025-09-28

  Explore the Influenza Hemagglutinin (HA) Peptide as a versatile protein purification tag and advanced epitope tag for protein detection. This article uniquely examines its physicochemical properties, mechanistic advantages, and strategic role in high-fidelity protein-protein interaction studies.

• X-press Tag Peptide: Precision Tagging for Neddylation an...

  2025-09-27

  Explore how X-press Tag Peptide empowers advanced protein purification and detection workflows, with a unique focus on neddylation and mTORC1 pathway studies. Discover in-depth technical insights, best practices, and innovative applications for this essential protein purification tag peptide.

• X-press Tag Peptide: Next-Generation Tools for Dynamic Pr...

  2025-09-26

  Explore how X-press Tag Peptide, a leading N-terminal leader peptide for protein purification, advances research by enabling precise detection and functional analysis of recombinant proteins. This article uncovers novel insights into integrating tag-based purification with investigation of cellular signaling pathways, including mTORC1 and neddylation.

• c-Myc tag Peptide: Advanced Roles in Cellular Regulation ...

  2025-09-25

  Explore the multifaceted roles of the c-Myc tag Peptide in transcription factor regulation, immunoassay optimization, and cancer biology. This in-depth article reveals advanced mechanistic insights and unique research applications that distinguish it from prior content.

• c-Myc tag Peptide: Next-Gen Insights for Oncogenic Pathwa...

  2025-09-24

  Explore the advanced scientific and mechanistic roles of the c-Myc tag Peptide in cancer biology, focusing on its unique ability to dissect proto-oncogene c-Myc regulation and gene amplification. This article provides a deep dive into peptide-enabled research strategies, standing apart with novel perspectives on transcription factor regulation in the context of emerging autophagy and immune signaling findings.

• X-press Tag Peptide: Streamlining Quantitative Protein In...

  2025-09-23

  Explore how X-press Tag Peptide, a versatile N-terminal leader peptide, advances quantitative protein interaction studies and affinity purification using ProBond resin. This article details practical strategies for peptide solubility, detection, and integration with modern post-translational modification research.

• FLAG tag Peptide (DYKDDDDK): Enhancing Precision in Recom...

  2025-09-22

  Explore the critical role o

• X-press Tag Peptide: Optimizing Epitope Tag Strategies in...

  2025-09-19

  Explore the multifaceted role of X-press Tag Peptide as an N-terminal leader peptide for affinity purification and detection in recombinant protein expression. This article examines technical considerations and recent applications, highlighting advances in protein purification tag peptide design and usage.

• X-press Tag Peptide: Enabling Advanced N-Terminal Tagging...

  2025-09-18

  This article explores the X-press Tag Peptide as an N-terminal leader peptide engineered for high-specificity protein purification, focusing on its role in epitope tagging, detection, and controlled cleavage. By integrating recent research advances and technical insights, it highlights how X-press Tag Peptide advances affinity purification using ProBond resin and facilitates robust protein analysis.

• These mutations induce the gene auto

  2025-03-03

  

  These mutations induce the gene auto-activation in 10–40% of adenocarcinomas, triggering the EGFR-signaling pathway in the absence of ligand. That leads to an uncontrolled acceleration of cell proliferation, survival and anti-apoptotic signals (Couraud et al., 2012). The frequency of these mutations

• NLX a k a F or befiradol exhibits

  2025-03-03

  

  NLX-112 (a.k.a. F13640 or befiradol), exhibits nanomolar affinity at 5-HT1A receptors, and, in ep4 antagonist to the 5-HT1A receptor agonists listed above, it presents exceptional selectivity and high efficacy at these receptors (Colpaert et al., 2002, Newman-Tancredi et al., 2017). Additionally, it

• The anorexic effect observed when AR is

  2025-03-03

  

  The anorexic effect observed when AR231630 is infused into the VTA could be the result of the DA release inhibition, as previously described [11]. However, there is also a hedonic aspect in feeding that possibly involves dopaminergic mechanisms of reward. Helm et al. showed a functional link between

• In the late s Solvay Pharmaceuticals discontinued the Phase

  2025-03-03

  

  In the late ‘90s, Solvay Pharmaceuticals discontinued the Phase 2 development of a promising potent and highly selective A1AR antagonist based on the pyrrolopyrimidine scaffold, SLV320 [43] (2, Chart 1, also named derenofylline; Ki hA1AR = 1 nM), for the treatment of acute heart failure [24]. In the

• Axl has been reported to mediate cell cell adhesion and

  2025-03-03

  

  Axl has been reported to mediate cell-cell adhesion and sphere-growth [11], [18] and to be important for metastasis to secondary organs [12], [14], [20]. We found an Axl-dependent CCRCC-ability of sphere-formation and repopulation after non-adhesive growth. Axl-inhibited cells could not attach to ea

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